Obesity, type 2 diabetes, and cancer: the insulin and IGF connection

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Obesity, type 2 diabetes, and cancer: the insulin and IGF connection.

Epidemiological studies suggest a positive association between obesity and type 2 diabetes mellitus (T2D) with the risk of cancer and cancer-related mortality. Insulin resistance, hyperinsulinemia, increased levels of IGF, elevated levels of steroid and peptide hormones, and inflammatory markers appear to play a role in the connection between these different diseases. Medications, such as metfo...

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Exenatide therapy in insulin-treated type 2 diabetes and obesity.

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9. Babbs C, Warnes TW, Torrance HB, Ballardie FW. IgA nephro17. Lomax-Smith JD, Zabrowarny LA, Howarth GS, Seymour pathy in non-cirrhotic portal hypertension. Gut 1990; 32: AAE, Woodroffe AJ. The immunochemical characterisation of 225–226 mesangial IgA deposits. Am J Pathol 1983; 113: 359–364 10. Berger J, Yaneva H, Nabarra B. Glomerular changes in patients 18. Giron JA, Alvarez-Mon M, Menéndez...

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ژورنال

عنوان ژورنال: Endocrine-Related Cancer

سال: 2012

ISSN: 1351-0088,1479-6821

DOI: 10.1530/erc-11-0374